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Self-reflection is linked to improved cognition in later life and brain health

Summary: A new study finds that a person’s ability to self-reflex is linked to cognition and glucose metabolism later in life. Those who engage in more self-reflection have improved cognition, better overall brain health, and increased glucose metabolism later in life.

source: UCL

A new study led by UCLA researchers has found that self-reflection is positively associated with cognition later in life as well as glucose metabolism, a marker of brain health.

The authors of the new study published in Neurologysuppose that older adults who engage in self-reflection may have a lower risk of developing dementia.

Lead author, Ph.D. “There is a growing body of evidence to find that positive psychological factors, such as purpose in life and conscience, may reduce the risk of dementia,” says student Harriet Demnitz King (UCL Psychiatry).

Finding other ways to reduce dementia risk is an urgent priority, so we hope that self-reflection abilities can be improved, as it can be a useful tool in helping people stay cognitively healthy as they age.”

“A person can engage in self-reflection and possibly increase their amount of self-reflection, because it does not depend on physical health or socioeconomic factors.”

The study used cross-sectional data (rather than reporting results of empirical interventions) from two clinical trials, Age-Well and SCD-Well, which included a total of 259 participants with average ages of 69 and 73. They answered questions about meditation reversal, and measured how often They think about it and try to understand their thoughts and feelings.

The researchers found that people who engaged more in self-reflection had better cognition and improved glucose metabolism as evidenced by brain imaging. The researchers found no association with amyloid deposition, which is the buildup of harmful brain proteins linked to Alzheimer’s disease.

Previous research has shown that self-reflection abilities can be improved with a recently tested psychological intervention, and researchers say such a program may be beneficial for people at risk of developing dementia.

Harriet Demnitz-King explained, “Other studies have found that reflexology leads to a more adaptive response to stress, with evidence showing improved inflammatory responses to stress and improved cardiovascular health, so this may be how self-reflection can improve our resilience against stress.” cognitive decline”.

They caution that while their findings suggest that engaging in self-reflection helps maintain cognition, they cannot rule out that people with better cognition may also be more capable of self-reflection, and suggest that more longitudinal research is needed. To determine the direction of causation.

Senior author Dr. Natalie Marchant (UCL Psychiatry) says, “With disease-modifying therapies not yet available, it is important that we find ways to prevent dementia. By discovering factors that increase or decrease the likelihood of dementia or cognitive decline, we may be able to develop ways to prevent dementia. To target these factors and reduce the risk of dementia.”

“Self-reflection has also been associated with other benefits, such as recovery from depression and improved cardiovascular health, so even if we can’t confirm how it affects cognitive decline, there is other evidence to show its overall benefits.”

The researchers found that people who engaged more in self-reflection had better cognition and improved glucose metabolism as evidenced by brain imaging. The image is in the public domain

Previous studies by Dr. Marchant have found that frequent negative thinking may increase the risk of Alzheimer’s disease, while mindfulness may help improve cognition in older adults.

Richard Oakley, associate director of research at the Alzheimer’s Society, commented: “In this study, researchers have shown for the first time that self-reflection – reflecting your thoughts, feelings, and behaviors – is associated with better brain function in areas of the brain known to be affected by dementia.”

“While more research is needed to fully understand the implications of this finding, if self-reflection appears to have a positive effect on brain function, there is a chance that one day we can reduce the risk of dementia through psychological therapies that help people on building healthy .patterns of thinking.”

“The number of people living with dementia in the UK is set to rise to 1.6 million by 2040 – the Government’s commitment to double funding for dementia research will ensure researchers explore every avenue to reduce risk.”

About this aging news and self-reflection

author: Chris Lynn
source: UCL
Contact: Chris Lynn – UCL
picture: The image is in the public domain

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The relationship between self-reflection, cognition, and brain health in older adults without cognitive impairmentsWritten by Harriet Demnitz King et al. Neurology


Summary

The relationship between self-reflection, cognition, and brain health in older adults without cognitive impairments

Background and goals: Self-reflection (the active evaluation of an individual’s thoughts, feelings, and behaviors) can provide protection against adverse health outcomes. However, its effect on sensitive markers of Alzheimer’s disease (AD) is unknown. The primary objective of this cross-sectional study was to examine the relationship between autonomic reflexology and sensitive markers of Alzheimer’s disease.

Methods: This study used baseline data from non-cognitively impaired older adults enrolled in the Age-Well clinical trial and older adults with subjective cognitive decline from the SCD-Well clinical trial. In both groups, self-reflection was measured via the Rumination Response Scale Subscale Reflection, Global Cognition Assessed via the Preclinical Alzheimer’s Disease Cognitive Compound 5, and the LATE Brain Health Adjusted Lifestyle Index (LIBRA) computed on the assessment of health and lifestyle factors.

In Age-Well, glucose metabolism and amyloid deposition in AD-sensitive gray matter regions were quantified via FDG- and AV45-PET assays, respectively. Associations between self-reflection and sensitive markers of Alzheimer’s disease (global cognition, glucose metabolism, and amyloid deposition) were assessed by unadjusted and adjusted regressions. Furthermore, we explored whether the associations were independent of health and lifestyle factors. To control for multiple comparisons in Age-Well, the false discovery rate was corrected s-Value (sFranklin Roosevelt) A report has been made.

consequences: A total of 134 (mean age 69.3 ± 3.8 years, 61.9% female) Age-Well and 125 (mean age 72.6 ± 6.9 years, 65.6% female) SCD-Well participants were included. Across unadjusted and adjusted analyses, self-reflection was positively associated with global cognition in both groups (Age-Well: Adjust-B = 0.22, 95% confidence interval [CI] 0.05-0.40, sFranklin Roosevelt = 0.041; SCD- OK: Edit-B = 0.18And the 95% CI 0.03-0.33, s = 0.023) and with Age-Well glucose metabolism after adjustment for all covariates (adjusted-B = 0.29, 95% CI 0.03-0.55, sFranklin Roosevelt = 0.041). The associations remained after an additional modification of LIBRA but did not survive the FDR correction. Autoreflex was not associated with amyloid deposition (modified-B = 0.13, 95% CI -0.07-0.34, sFranklin Roosevelt = 0.189).

Discuss: Self-reflection was associated with better global cognition in two independent groups and with higher glucose metabolism after adjusting for covariates. There was weak evidence that relationships were independent of health behaviors and lifestyles. Longitudinal and experimental studies are warranted to clarify whether autoreflex helps maintain cognition and glucose metabolism, or whether reduced autoreflexive capacity is a harbinger of cognitive decline and decreased glucose metabolism.

Trial recording: age well: NCT02977819; SCD- ok: NCT03005652

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